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DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3
Pre–B and pre–T lymphocytes must orchestrate a transition from a highly proliferative state to a quiescent one during development. Cyclin D3 is essential for these cells’ proliferation, but little is known about its posttranslational regulation at this stage. Here, we show that the dual specificity...
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| Pubblicato in: | J Exp Med |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451127/ https://ncbi.nlm.nih.gov/pubmed/26008897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150002 |
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