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Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part II

The convenient synthesis of a focused library (forty molecules) of novel 6,6,5-tricyclic thiazolo[5,4-f]quinazolines was realized mainly under microwave irradiation. A novel 6-aminobenzo[d]thiazole-2,7-dicarbonitrile (1) was used as a versatile molecular platform for the synthesis of various derivat...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Foucourt, Alicia, Hédou, Damien, Dubouilh-Benard, Carole, Girard, Angélique, Taverne, Thierry, Casagrande, Anne-Sophie, Désiré, Laurent, Leblond, Bertrand, Besson, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271009/
https://ncbi.nlm.nih.gov/pubmed/25264830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191015411
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