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Promiscuity progression of bioactive compounds over time

In the context of polypharmacology, compound promiscuity is rationalized as the ability of small molecules to specifically interact with multiple targets. To study promiscuity progression of bioactive compounds in detail, nearly 1 million compounds and more than 5.2 million activity records were ana...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:F1000Res
Hauptverfasser: Hu, Ye, Jasial, Swarit, Bajorath, Jürgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: F1000Research 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448747/
https://ncbi.nlm.nih.gov/pubmed/26064479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.6473.1
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