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Promiscuity progression of bioactive compounds over time

In the context of polypharmacology, compound promiscuity is rationalized as the ability of small molecules to specifically interact with multiple targets. To study promiscuity progression of bioactive compounds in detail, nearly 1 million compounds and more than 5.2 million activity records were ana...

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Библиографические подробности
Опубликовано в: :F1000Res
Главные авторы: Hu, Ye, Jasial, Swarit, Bajorath, Jürgen
Формат: Artigo
Язык:Inglês
Опубликовано: F1000Research 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448747/
https://ncbi.nlm.nih.gov/pubmed/26064479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.6473.1
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