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What is the Likelihood of an Active Compound to Be Promiscuous? Systematic Assessment of Compound Promiscuity on the Basis of PubChem Confirmatory Bioassay Data

Compound promiscuity refers to the ability of small molecules to specifically interact with multiple targets, which represents the origin of polypharmacology. Promiscuity is thought to be a widespread characteristic of pharmaceutically relevant compounds. Yet, the degree of promiscuity among active...

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Detaylı Bibliyografya
Asıl Yazarlar: Hu, Ye, Bajorath, Jürgen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691425/
https://ncbi.nlm.nih.gov/pubmed/23605807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9488-0
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