Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins

RNA binding proteins of the conserved CUGBP1, Elav-like factor (CELF) family contribute to heart and skeletal muscle development and are implicated in myotonic dystrophy (DM). To understand their genome-wide functions, we analyzed the transcriptome dynamics following induction of CELF1 or CELF2 in a...

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Foilsithe in:Genome Res
Main Authors: Wang, Eric T., Ward, Amanda J., Cherone, Jennifer M., Giudice, Jimena, Wang, Thomas T., Treacy, Daniel J., Lambert, Nicole J., Freese, Peter, Saxena, Tanvi, Cooper, Thomas A., Burge, Christopher B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2015
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448682/
https://ncbi.nlm.nih.gov/pubmed/25883322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.184390.114
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