Identification of MBNL1 and MBNL3 domains required for splicing activation and repression

Muscleblind-like 1 (MBNL1) is a splicing regulator that controls developmentally regulated alternative splicing of a large number of exons including exon 11 of the Insulin Receptor (IR) gene and exon 5 of the cardiac Troponin T (cTNT) gene. There are three paralogs of MBNL in humans, all of which pr...

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Bibliographic Details
Main Authors: Grammatikakis, Ioannis, Goo, Young-Hwa, Echeverria, Gloria V., Cooper, Thomas A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074124/
https://ncbi.nlm.nih.gov/pubmed/21109529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1155
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