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Antagonistic regulation of α-actinin alternative splicing by CELF proteins and polypyrimidine tract binding protein

The α-actinin gene has a pair of alternatively spliced exons. The smooth muscle (SM) exon is repressed in most cell types by polypyrimidine tract binding protein (PTB). CELF (CUG-BP and ETR3-like factors) family proteins, splicing regulators whose activities are altered in myotonic dystrophy, were f...

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Detalhes bibliográficos
Main Authors: GROMAK, NATALIA, MATLIN, ARIANNE J., COOPER, THOMAS A., SMITH, CHRISTOPHER W.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2003 by RNA Society 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370411/
https://ncbi.nlm.nih.gov/pubmed/12649496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2191903
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