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The polypyrimidine tract binding protein regulates desaturase alternative splicing and PUFA composition

The Δ6 desaturase, encoded by FADS2, plays a crucial role in omega-3 and omega-6 fatty acid synthesis. These fatty acids are essential components of the central nervous system, and they act as precursors for eicosanoid signaling molecules and as direct modulators of gene expression. The polypyrimidi...

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Detalhes bibliográficos
Main Authors: Reardon, Holly T., Park, Woo Jung, Zhang, Jimmy, Lawrence, Peter, Kothapalli, Kumar S. D., Brenna, J. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220295/
https://ncbi.nlm.nih.gov/pubmed/21980057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M019653
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