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Repression of α-actinin SM exon splicing by assisted binding of PTB to the polypyrimidine tract

Polypyrimidine tract binding protein (PTB) acts as a regulatory repressor of a large number of alternatively spliced exons, often requiring multiple binding sites in order to repress splicing. In one case, cooperative binding of PTB has been shown to accompany repression. The SM exon of the α-actini...

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Detalhes bibliográficos
Main Authors: Matlin, Arianne J., Southby, Justine, Gooding, Clare, Smith, Christopher W.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924891/
https://ncbi.nlm.nih.gov/pubmed/17592047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.219607
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