Reactive Nitrogen Species-Induced Cell Death Requires Fas-Dependent Activation of c-Jun N-Terminal Kinase

Nitrogen dioxide is a highly toxic reactive nitrogen species (RNS) recently discovered as an inflammatory oxidant with great potential to damage tissues. We demonstrate here that cell death by RNS was caused by c-Jun N-terminal kinase (JNK). Activation of JNK by RNS was density dependent and caused...

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Detalhes bibliográficos
Main Authors: Shrivastava, Punya, Pantano, Cristen, Watkin, Richard, McElhinney, Brian, Guala, Amy, Poynter, Matthew L., Persinger, Rebecca L., Budd, Ralph, Janssen-Heininger, Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444859/
https://ncbi.nlm.nih.gov/pubmed/15254243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.15.6763-6772.2004
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