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Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-β1

Transforming growth factor β1 (TGF-β1) is a cardinal cytokine in the pathogenesis of airway remodeling, and promotes epithelial-to-mesenchymal transition (EMT). As a molecular interaction between TGF-β1 and Jun N-terminal kinase (JNK) has been demonstrated, the goal of this study was to elucidate wh...

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Hlavní autoři: Alcorn, John F., Guala, Amy S., Velden, Jos van der, McElhinney, Brian, Irvin, Charles G., Davis, Roger J., Janssen-Heininger, Yvonne M. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876720/
https://ncbi.nlm.nih.gov/pubmed/18334556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.019455
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