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Distinct Functions of Airway Epithelial Nuclear Factor-κB Activity Regulate Nitrogen Dioxide–Induced Acute Lung Injury

Reactive oxidants such as nitrogen dioxide (NO(2)) injure the pulmonary epithelium, causing airway damage and inflammation. We previously demonstrated that nuclear factor-κ B (NF-κB) activation within airway epithelial cells occurs in response to NO(2) inhalation, and is critical for lipopolysacchar...

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Detalhes bibliográficos
Main Authors: Ather, Jennifer L., Alcorn, John F., Brown, Amy L., Guala, Amy S., Suratt, Benjamin T., Janssen-Heininger, Yvonne M. W., Poynter, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951874/
https://ncbi.nlm.nih.gov/pubmed/19901348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0416OC
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