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Nuclear Factor-κB Activation in Airway Epithelium Induces Inflammation and Hyperresponsiveness

Rationale: Nuclear factor (NF)-κB is a prominent proinflammatory transcription factor that plays a critical role in allergic airway disease. Previous studies demonstrated that inhibition of NF-κB in airway epithelium causes attenuation of allergic inflammation. Objectives: We sought to determine if...

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Detalhes bibliográficos
Main Authors: Pantano, Cristen, Ather, Jennifer L., Alcorn, John F., Poynter, Matthew E., Brown, Amy L., Guala, Amy S., Beuschel, Stacie L., Allen, Gilman B., Whittaker, Laurie A., Bevelander, Mieke, Irvin, Charles G., Janssen-Heininger, Yvonne M. W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361423/
https://ncbi.nlm.nih.gov/pubmed/18263801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200707-1096OC
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