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Transforming Growth Factor-β1 Suppresses Airway Hyperresponsiveness in Allergic Airway Disease

Rationale: Asthma is characterized by increases in airway resistance, pulmonary remodeling, and lung inflammation. The cytokine transforming growth factor (TGF)-β has been shown to have a central role in asthma pathogenesis and in mouse models of allergic airway disease. Objectives: To determine the...

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Main Authors: Alcorn, John F., Rinaldi, Lisa M., Jaffe, Elizabeth F., van Loon, Mirjam, Bates, Jason H. T., Janssen-Heininger, Yvonne M. W., Irvin, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2078678/
https://ncbi.nlm.nih.gov/pubmed/17761617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200702-334OC
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