Allergic Sensitization through the Airway Primes Th17-dependent Neutrophilia and Airway Hyperresponsiveness

Rationale: In humans, immune responses to inhaled aeroallergens develop in the lung and draining lymph nodes. Many animal models of asthma bypass this route and instead use intraperitoneal injections of allergen using aluminum hydroxide as an adjuvant. Objectives: We investigated whether allergic se...

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Detalhes bibliográficos
Main Authors: Wilson, Rhonda H., Whitehead, Gregory S., Nakano, Hideki, Free, Meghan E., Kolls, Jay K., Cook, Donald N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
B. Asthma and Allergy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778149/
https://ncbi.nlm.nih.gov/pubmed/19661246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200904-0573OC
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