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Airway Hyperresponsiveness in Allergically Inflamed Mice: The Role of Airway Closure

Rationale: Allergically inflamed mice exhibit airway hyperresponsiveness to inhaled methacholine, which computer simulations of lung impedance suggest is due to enhanced lung derecruitment and which we sought to verify in the present study. Methods: BALB/c mice were sensitized and challenged with ov...

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Main Authors: Lundblad, Lennart K. A., Thompson-Figueroa, John, Allen, Gilman B., Rinaldi, Lisa, Norton, Ryan J., Irvin, Charles G., Bates, Jason H. T.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899295/
https://ncbi.nlm.nih.gov/pubmed/17255559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200610-1410OC
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