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IL-35 Production by ICOS(+) Tregs Reverses Established IL-17-dependent Allergic Airways Disease

BACKGROUND: Recent evidence suggests that IL-17 contributes to airway hyperresponsiveness (AHR); however, the mechanisms that suppress the production of this cytokine remain poorly defined. OBJECTIVES: We sought to understand the cellular and molecular basis for suppression of established, IL-17-dep...

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Detalhes bibliográficos
Main Authors: Whitehead, Gregory S., Wilson, Rhonda H., Nakano, Keiko, Burch, Lauranell H., Nakano, Hideki, Cook, Donald N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269135/
https://ncbi.nlm.nih.gov/pubmed/21906794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.08.009
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