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TNF is required for TLR ligand–mediated but not protease-mediated allergic airway inflammation

Asthma is associated with exposure to a wide variety of allergens and adjuvants. The extent to which overlap exists between the cellular and molecular mechanisms triggered by these various agents is poorly understood, but it might explain the differential responsiveness of patients to specific thera...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Whitehead, Gregory S., Thomas, Seddon Y., Shalaby, Karim H., Nakano, Keiko, Moran, Timothy P., Ward, James M., Flake, Gordon P., Nakano, Hideki, Cook, Donald N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669552/
https://ncbi.nlm.nih.gov/pubmed/28758900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90890
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