Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas

Reactive oxygen species (ROS) increase ligation of Fas (CD95), a receptor important for regulation of programmed cell death. Glutathionylation of reactive cysteines represents an oxidative modification that can be reversed by glutaredoxins (Grxs). The goal of this study was to determine whether Fas...

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Main Authors: Anathy, Vikas, Aesif, Scott W., Guala, Amy S., Havermans, Marije, Reynaert, Niki L., Ho, Ye-Shih, Budd, Ralph C., Janssen-Heininger, Yvonne M.W.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2009
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654302/
https://ncbi.nlm.nih.gov/pubmed/19171757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200807019
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