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Cigarette Smoke Targets Glutaredoxin 1, Increasing S-Glutathionylation and Epithelial Cell Death

It is established that cigarette smoke (CS) causes irreversible oxidations in lung epithelial cells, and can lead to their death. However, its impact on reversible and physiologically relevant redox-dependent protein modifications remains to be investigated. Glutathione is an important antioxidant a...

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Bibliografiske detaljer
Main Authors: Kuipers, Ine, Guala, Amy S., Aesif, Scott W., Konings, Gonda, Bouwman, Freek G., Mariman, Edwin C., Wouters, Emiel F. M., Janssen-Heininger, Yvonne M. W., Reynaert, Niki L.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262689/
https://ncbi.nlm.nih.gov/pubmed/21454804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0249OC
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