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Increasing Fragmentation of Disulfide-Bonded Proteins for Top-Down Mass Spectrometry by Supercharging

The disulfide bond is an important post-translational modification to form and maintain the native structure and biological functions of proteins. Characterization of disulfide bond linkages is therefore of essential interest in the structural elucidation of proteins. Top-down mass spectrometry (MS)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mass Spectrom
Main Authors: Zhang, Jiang, Ogorzalek Loo, Rachel R., Loo, Joseph A.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448141/
https://ncbi.nlm.nih.gov/pubmed/26028988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2014.07.047
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