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Internal fragments generated by electron ionization dissociation enhance protein top-down mass spectrometry

Top-down proteomics by mass spectrometry (MS) involves the mass measurement of an intact protein followed by subsequent activation of the protein to generate product ions. Electron-based fragmentation methods like electron capture dissociation (ECD) and electron transfer dissociation (ETD) are widel...

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Bibliografiset tiedot
Julkaisussa:J Am Soc Mass Spectrom
Päätekijät: Zenaidee, Muhammad A., Lantz, Carter, Perkins, Taylor, Jung, Wonhyuek, Ogorzalek Loo, Rachel R., Loo, Joseph A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485267/
https://ncbi.nlm.nih.gov/pubmed/32799534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.0c00160
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