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Internal fragments generated by electron ionization dissociation enhance protein top-down mass spectrometry
Top-down proteomics by mass spectrometry (MS) involves the mass measurement of an intact protein followed by subsequent activation of the protein to generate product ions. Electron-based fragmentation methods like electron capture dissociation (ECD) and electron transfer dissociation (ETD) are widel...
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| Veröffentlicht in: | J Am Soc Mass Spectrom |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7485267/ https://ncbi.nlm.nih.gov/pubmed/32799534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.0c00160 |
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