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Top-Down Mass Spectrometry of Supercharged Native Protein-Ligand Complexes

Tandem mass spectrometry (MS/MS) of intact, noncovalently-bound protein-ligand complexes can yield structural information on the site of ligand binding. Fourier transform ion cyclotron resonance (FT-ICR) top-down MS of the 29 kDa carbonic anhydrase-zinc complex and adenylate kinase bound to adenosin...

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Sonraí Bibleagrafaíochta
Main Authors: Yin, Sheng, Loo, Joseph A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076692/
https://ncbi.nlm.nih.gov/pubmed/21499519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2010.06.032
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