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Top-Down Mass Spectrometry of Supercharged Native Protein-Ligand Complexes
Tandem mass spectrometry (MS/MS) of intact, noncovalently-bound protein-ligand complexes can yield structural information on the site of ligand binding. Fourier transform ion cyclotron resonance (FT-ICR) top-down MS of the 29 kDa carbonic anhydrase-zinc complex and adenylate kinase bound to adenosin...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076692/ https://ncbi.nlm.nih.gov/pubmed/21499519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2010.06.032 |
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