A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma

Recent advances in genetics have spurred rapid progress towards the systematic identification of genes involved in complex diseases. Still, the detailed understanding of the molecular and physiological mechanisms through which these genes affect disease phenotypes remains a major challenge. Here, we...

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Publicado en:Hum Mol Genet
Main Authors: Sharma, Amitabh, Menche, Jörg, Huang, C. Chris, Ort, Tatiana, Zhou, Xiaobo, Kitsak, Maksim, Sahni, Nidhi, Thibault, Derek, Voung, Linh, Guo, Feng, Ghiassian, Susan Dina, Gulbahce, Natali, Baribaud, Frédéric, Tocker, Joel, Dobrin, Radu, Barnathan, Elliot, Liu, Hao, Panettieri, Reynold A., Tantisira, Kelan G., Qiu, Weiliang, Raby, Benjamin A., Silverman, Edwin K., Vidal, Marc, Weiss, Scott T., Barabási, Albert-László
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447811/
https://ncbi.nlm.nih.gov/pubmed/25586491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv001
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