Pharmacologic targeting of sirtuin and PPAR signaling improves longevity and mitochondrial physiology in respiratory chain complex I mutant Caenorhabditis elegans

Antzeko izenburuak

• Molecular profiling of mitochondrial dysfunction in Caenorhabditis elegans
  nork: Polyak, Erzsebet, et al.
  Argitaratua: (2012)
• Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans
  nork: Dingley, Stephen, et al.
  Argitaratua: (2009)
• N-acetylcysteine and vitamin E rescue animal longevity and cellular oxidative stress in preclinical models of mitochondrial complex I disease
  nork: Polyak, Erzsebet, et al.
  Argitaratua: (2018)
• Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism
  nork: Chapman, Kimberly A., et al.
  Argitaratua: (2017)
• Combinatorial glucose, nicotinic acid and N-acetylcysteine therapy has synergistic effect in preclinical C. elegans and zebrafish models of mitochondrial complex I disease
  nork: Guha, Sujay, et al.
  Argitaratua: (2021)