Summary of the DREAM8 Parameter Estimation Challenge: Toward Parameter Identification for Whole-Cell Models

Whole-cell models that explicitly represent all cellular components at the molecular level have the potential to predict phenotype from genotype. However, even for simple bacteria, whole-cell models will contain thousands of parameters, many of which are poorly characterized or unknown. New algorith...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Karr, Jonathan R., Williams, Alex H., Zucker, Jeremy D., Raue, Andreas, Steiert, Bernhard, Timmer, Jens, Kreutz, Clemens, Wilkinson, Simon, Allgood, Brandon A., Bot, Brian M., Hoff, Bruce R., Kellen, Michael R., Covert, Markus W., Stolovitzky, Gustavo A., Meyer, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Perspective
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447414/
https://ncbi.nlm.nih.gov/pubmed/26020786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004096
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