Driving the Model to Its Limit: Profile Likelihood Based Model Reduction

In systems biology, one of the major tasks is to tailor model complexity to information content of the data. A useful model should describe the data and produce well-determined parameter estimates and predictions. Too small of a model will not be able to describe the data whereas a model which is to...

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Publicado en:PLoS One
Autores principales: Maiwald, Tim, Hass, Helge, Steiert, Bernhard, Vanlier, Joep, Engesser, Raphael, Raue, Andreas, Kipkeew, Friederike, Bock, Hans H., Kaschek, Daniel, Kreutz, Clemens, Timmer, Jens
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010240/
https://ncbi.nlm.nih.gov/pubmed/27588423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162366
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