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Likelihood based observability analysis and confidence intervals for predictions of dynamic models

BACKGROUND: Predicting a system’s behavior based on a mathematical model is a primary task in Systems Biology. If the model parameters are estimated from experimental data, the parameter uncertainty has to be translated into confidence intervals for model predictions. For dynamic models of biochemic...

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Bibliografische gegevens
Hoofdauteurs: Kreutz, Clemens, Raue, Andreas, Timmer, Jens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490710/
https://ncbi.nlm.nih.gov/pubmed/22947028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-120
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