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Likelihood based observability analysis and confidence intervals for predictions of dynamic models

BACKGROUND: Predicting a system’s behavior based on a mathematical model is a primary task in Systems Biology. If the model parameters are estimated from experimental data, the parameter uncertainty has to be translated into confidence intervals for model predictions. For dynamic models of biochemic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kreutz, Clemens, Raue, Andreas, Timmer, Jens
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490710/
https://ncbi.nlm.nih.gov/pubmed/22947028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-120
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