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Likelihood based observability analysis and confidence intervals for predictions of dynamic models

BACKGROUND: Predicting a system’s behavior based on a mathematical model is a primary task in Systems Biology. If the model parameters are estimated from experimental data, the parameter uncertainty has to be translated into confidence intervals for model predictions. For dynamic models of biochemic...

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Detalhes bibliográficos
Main Authors: Kreutz, Clemens, Raue, Andreas, Timmer, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490710/
https://ncbi.nlm.nih.gov/pubmed/22947028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-120
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