Network topology and parameter estimation: from experimental design methods to gene regulatory network kinetics using a community based approach

BACKGROUND: Accurate estimation of parameters of biochemical models is required to characterize the dynamics of molecular processes. This problem is intimately linked to identifying the most informative experiments for accomplishing such tasks. While significant progress has been made, effective exp...

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Detalhes bibliográficos
Main Authors: Meyer, Pablo, Cokelaer, Thomas, Chandran, Deepak, Kim, Kyung Hyuk, Loh, Po-Ru, Tucker, George, Lipson, Mark, Berger, Bonnie, Kreutz, Clemens, Raue, Andreas, Steiert, Bernhard, Timmer, Jens, Bilal, Erhan, DREAM 6&7 Parameter Estimation consortium, Sauro, Herbert M, Stolovitzky, Gustavo, Saez-Rodriguez, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927870/
https://ncbi.nlm.nih.gov/pubmed/24507381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-13
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