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Characterization of the Binding of Amphotericin B to Saccharomyces cerevisiae and Relationship to the Antifungal Effects

Based on the enhanced fluorescence of amphotericin B in acid solutions, a quantitative assay for this polyene antibiotic has been developed that is sensitive and linear in the range of 0.1 to 10.0 μM. The binding of amphotericin B to Saccharomyces cerevisiae was assayed under various conditions as t...

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Detalles Bibliográficos
Main Authors: Kotler-Brajtburg, Janina, Medoff, Gerald, Schlessinger, David, Kobayashi, George S.
Formato: Artigo
Idioma:Inglês
Publicado: 1974
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC444734/
https://ncbi.nlm.nih.gov/pubmed/4615631
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