Characterization of the Binding of Amphotericin B to Saccharomyces cerevisiae and Relationship to the Antifungal Effects

Based on the enhanced fluorescence of amphotericin B in acid solutions, a quantitative assay for this polyene antibiotic has been developed that is sensitive and linear in the range of 0.1 to 10.0 μM. The binding of amphotericin B to Saccharomyces cerevisiae was assayed under various conditions as t...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Kotler-Brajtburg, Janina, Medoff, Gerald, Schlessinger, David, Kobayashi, George S.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1974
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4615631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.6.6.770
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