Classification of Polyene Antibiotics According to Chemical Structure and Biological Effects

Fourteen polyene antibiotics and six of their semisynthetic derivatives were compared for their effects on potassium (K(+)) leakage and lethality or hemolysis of either Saccharomyces cerevisiae or mouse erythrocytes. These polyene antibiotics fell into two groups. Group I antibiotics caused K(+) lea...

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Dades bibliogràfiques
Autors principals: Kotler-Brajtburg, J., Medoff, G., Kobayashi, G. S., Boggs, S., Schlessinger, D., Pandey, R. C., Rinehart, K. L.
Format: Artigo
Idioma:Inglês
Publicat: 1979
Matèries:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC352743/
https://ncbi.nlm.nih.gov/pubmed/393163
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