Classification of Polyene Antibiotics According to Chemical Structure and Biological Effects

Fourteen polyene antibiotics and six of their semisynthetic derivatives were compared for their effects on potassium (K(+)) leakage and lethality or hemolysis of either Saccharomyces cerevisiae or mouse erythrocytes. These polyene antibiotics fell into two groups. Group I antibiotics caused K(+) lea...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kotler-Brajtburg, J., Medoff, G., Kobayashi, G. S., Boggs, S., Schlessinger, D., Pandey, R. C., Rinehart, K. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1979
Assuntos:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/393163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.5.716
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