Wird geladen...

Antifolate Activity of Isoaminopterin in HeLa Cells

The antifolate activity and the transport characteristics of isoaminopterin (IA) in HeLa cells were studied and compared with those of methotrexate (MTX). Both IA and MTX inhibited the incorporation of [2-(14)C]deoxyuridine into HeLa cell DNA by 50% at a concentration of 0.09 μM by 8 h postaddition...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Rosemond-Hornbeak, Hortencia, Nair, M. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1979
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC352745/
https://ncbi.nlm.nih.gov/pubmed/525990
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!