Antifolate Activity of Isoaminopterin in HeLa Cells
The antifolate activity and the transport characteristics of isoaminopterin (IA) in HeLa cells were studied and compared with those of methotrexate (MTX). Both IA and MTX inhibited the incorporation of [2-(14)C]deoxyuridine into HeLa cell DNA by 50% at a concentration of 0.09 μM by 8 h postaddition...
Guardado en:
| Publicado en: | Antimicrob Agents Chemother |
|---|---|
| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1979
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/525990/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.5.730 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|