Antifolate Activity of Isoaminopterin in HeLa Cells
The antifolate activity and the transport characteristics of isoaminopterin (IA) in HeLa cells were studied and compared with those of methotrexate (MTX). Both IA and MTX inhibited the incorporation of [2-(14)C]deoxyuridine into HeLa cell DNA by 50% at a concentration of 0.09 μM by 8 h postaddition...
保存先:
| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1979
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/525990/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.5.730 |
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