Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype

Mutations in the rhodopsin gene cause retinal degeneration and clinical phenotypes including retinitis pigmentosa (RP) and congenital stationary night blindness. Effective gene therapies have been difficult to develop, however, because generating precise levels of rhodopsin expression is critical; o...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Han, Zongchao, Banworth, Marcellus J., Makkia, Rasha, Conley, Shannon M., Al-Ubaidi, Muayyad R., Cooper, Mark J., Naash, Muna I.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447225/
https://ncbi.nlm.nih.gov/pubmed/25713057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-270363
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