Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype

Mutations in the rhodopsin gene cause retinal degeneration and clinical phenotypes including retinitis pigmentosa (RP) and congenital stationary night blindness. Effective gene therapies have been difficult to develop, however, because generating precise levels of rhodopsin expression is critical; o...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Han, Zongchao, Banworth, Marcellus J., Makkia, Rasha, Conley, Shannon M., Al-Ubaidi, Muayyad R., Cooper, Mark J., Naash, Muna I.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2015
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447225/
https://ncbi.nlm.nih.gov/pubmed/25713057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-270363
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