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Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype

Mutations in the rhodopsin gene cause retinal degeneration and clinical phenotypes including retinitis pigmentosa (RP) and congenital stationary night blindness. Effective gene therapies have been difficult to develop, however, because generating precise levels of rhodopsin expression is critical; o...

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Podrobná bibliografie
Vydáno v:FASEB J
Hlavní autoři: Han, Zongchao, Banworth, Marcellus J., Makkia, Rasha, Conley, Shannon M., Al-Ubaidi, Muayyad R., Cooper, Mark J., Naash, Muna I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447225/
https://ncbi.nlm.nih.gov/pubmed/25713057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-270363
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