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Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype

Mutations in the rhodopsin gene cause retinal degeneration and clinical phenotypes including retinitis pigmentosa (RP) and congenital stationary night blindness. Effective gene therapies have been difficult to develop, however, because generating precise levels of rhodopsin expression is critical; o...

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書目詳細資料
發表在:FASEB J
Main Authors: Han, Zongchao, Banworth, Marcellus J., Makkia, Rasha, Conley, Shannon M., Al-Ubaidi, Muayyad R., Cooper, Mark J., Naash, Muna I.
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447225/
https://ncbi.nlm.nih.gov/pubmed/25713057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-270363
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