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A Partial Structural and Functional Rescue of a Retinitis Pigmentosa Model with Compacted DNA Nanoparticles

Previously we have shown that compacted DNA nanoparticles can drive high levels of transgene expression after subretinal injection in the mouse eye. Here we delivered compacted DNA nanoparticles containing a therapeutic gene to the retinas of a mouse model of retinitis pigmentosa. Nanoparticles cont...

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Detalhes bibliográficos
Main Authors: Cai, Xue, Nash, Zack, Conley, Shannon M., Fliesler, Steven J., Cooper, Mark J., Naash, Muna I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669177/
https://ncbi.nlm.nih.gov/pubmed/19390689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005290
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