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AAV and Compacted DNA Nanoparticles for the Treatment of Retinal Disorders: Challenges and Future Prospects

Gene therapy based on delivery of viral and nonviral vectors has shown great promise for the treatment of human ocular diseases; however, limitations have consistently prevented its widespread clinical application. Viral vectors have generally been better in terms of efficiency but have safety conce...

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Detalhes bibliográficos
Main Authors: Han, Zongchao, Conley, Shannon M., Naash, Muna I.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109015/
https://ncbi.nlm.nih.gov/pubmed/21558483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6916
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