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Comparative Analysis of DNA Nanoparticles and AAVs for Ocular Gene Delivery
Gene therapy is a critical tool for the treatment of monogenic retinal diseases. However, the limited vector capacity of the current benchmark delivery strategy, adeno-associated virus (AAV), makes development of larger capacity alternatives, such as compacted DNA nanoparticles (NPs), critical. Here...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525534/ https://ncbi.nlm.nih.gov/pubmed/23272225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052189 |
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