DNA nanoparticles are safe and nontoxic in non-human primate eyes

INTRODUCTION: DNA nanoparticles (NPs) comprising polylysine conjugated to polyethylene glycol efficiently target murine photoreceptors and the retinal pigment epithelium (RPE) and lead to long-term phenotypic improvement in models of retinal degeneration. Advancing this technology requires testing i...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Kelley, Ryan A, Conley, Shannon M, Makkia, Rasha, Watson, Jamie N, Han, Zongchao, Cooper, Mark J, Naash, Muna I
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849385/
https://ncbi.nlm.nih.gov/pubmed/29563793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S157000
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