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The relationship of autophagy defects and cartilage damage during joint aging in a mouse model

OBJECTIVES: Aging is a main risk factor for osteoarthritis (OA), the most prevalent musculoskeletal disorder. Defects in autophagy, an essential cellular homeostasis mechanism, have recently been observed in OA articular cartilage. The objectives of this study were to establish the constitutive leve...

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Bibliografiske detaljer
Udgivet i:Arthritis Rheumatol
Main Authors: Caramés, Beatriz, Olmer, Merissa, Kiosses, William B., Lotz, Martin
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446178/
https://ncbi.nlm.nih.gov/pubmed/25708836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39073
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