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Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling

The ability to adapt to acute and chronic hypoxia is critical for cellular survival. Two established functional responses to hypoxia include the regulation of gene transcription by HIF (hypoxiainducible factor), and the constriction of pulmonary arteries in response to alveolar hypoxia. The mechanis...

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Vydáno v:Biochem J
Hlavní autoři: Sabharwal, Simran S., Waypa, Gregory B., Marks, Jeremy D., Schumacker, Paul T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445964/
https://ncbi.nlm.nih.gov/pubmed/24044889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130740
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