Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

Transcriptional activation of erythropoietin, glycolytic enzymes, and vascular endothelial growth factor occurs during hypoxia or in response to cobalt chloride (CoCl(2)) in Hep3B cells. However, neither the mechanism of cellular O(2) sensing nor that of cobalt is fully understood. We tested whether...

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Detalhes bibliográficos
Main Authors: Chandel, N. S., Maltepe, E., Goldwasser, E., Mathieu, C. E., Simon, M. C., Schumacker, P. T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21706/
https://ncbi.nlm.nih.gov/pubmed/9751731
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