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Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling

The ability to adapt to acute and chronic hypoxia is critical for cellular survival. Two established functional responses to hypoxia include the regulation of gene transcription by HIF (hypoxiainducible factor), and the constriction of pulmonary arteries in response to alveolar hypoxia. The mechanis...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Sabharwal, Simran S., Waypa, Gregory B., Marks, Jeremy D., Schumacker, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445964/
https://ncbi.nlm.nih.gov/pubmed/24044889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130740
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