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Insights into Cytokine–Receptor Interactions from Cytokine Engineering
Cytokines exert a vast array of immunoregulatory actions critical to human biology and disease. However, the desired immunotherapeutic effects of native cytokines are often mitigated by toxicity or lack of efficacy, either of which results from cytokine receptor pleiotropy and/or undesired activatio...
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| Publié dans: | Annu Rev Immunol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4445396/ https://ncbi.nlm.nih.gov/pubmed/25493332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-032713-120211 |
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